What is included in the cruise fare?

Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.

How far in advance should I book this cruise?

For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on MSC Virtuosa.

What documents do I need to board?

Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Sao Paulo may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.

Can I change or cancel my booking?

Change and cancellation policies depend on MSC Cruises's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.

What is a 22-night cruise like?

A 22-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from MSC Virtuosa. Pack for both formal nights and casual deck days.

MSC Virtuosa 22-night South America from Santos (Sao Paulo from Sao Paulo, Mar 25, 2028

MSC Cruises · MSC Virtuosa · Mar 25, 2028 – Apr 16, 2028

Visit Sao Paulo, Rio de Janeiro, Buzios, Brazil, Salvador, Brazil, Maceio and 7 more ports

Departure Sao Paulo

Return Livorno(Florence), Italy

Duration 22 Nights

From $1849 pp

Itinerary

Day 1

Sao Paulo Arrives 12:00 AM · Departs 6:00 PM
Day 2

Rio de Janeiro Arrives 9:00 AM · Departs 7:00 PM
Day 3

Buzios, Brazil Arrives 7:00 AM · Departs 6:00 PM
Day 4

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 5

Salvador, Brazil Arrives 9:00 AM · Departs 7:00 PM
Day 6

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 7

Maceio Arrives 7:00 AM · Departs 5:00 PM
Day 8

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 9

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 10

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 11

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 12

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 13

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 14

Santa Cruz de Tenerife Arrives 7:00 AM · Departs 5:00 PM
Day 15

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 16

Tangier Arrives 8:00 AM · Departs 7:00 PM
Day 17

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 18

Barcelona Arrives 7:00 AM · Departs 7:00 PM
Day 19

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 20

La Goulette Arrives 8:00 AM · Departs 6:00 PM
Day 21

Palermo (Monreale), Italy Arrives 8:00 AM · Departs 6:00 PM
Day 22

Naples (Pompeii), Italy Arrives 6:00 AM · Departs 5:00 PM
Day 23

Livorno(Florence), Italy Arrives 9:00 AM · Departs 12:00 AM

Cabin Prices

Prices as of 2026-10-19.

Prices per person, based on double occupancy in USD.

Inside $1849

Ocean View $2269

Balcony $2789

Suite $8069

Ports of Call

Sao Paulo
Rio de Janeiro
Buzios, Brazil
Salvador, Brazil
Maceio
Santa Cruz de Tenerife
Tangier
Barcelona
La Goulette
Palermo (Monreale), Italy
Naples (Pompeii), Italy
Livorno(Florence), Italy

About This Cruise

22-night MSC Cruises MSC Virtuosa cruise from Sao Paulo to Rio de Janeiro, Buzios, Brazil, Salvador, Brazil and Maceio Compare cabins from $1,849.

Cruise Line MSC Cruises

Ship MSC Virtuosa

Frequently asked questions

What is included in the cruise fare?: Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.
How far in advance should I book this cruise?: For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on MSC Virtuosa.
What documents do I need to board?: Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Sao Paulo may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.
Can I change or cancel my booking?: Change and cancellation policies depend on MSC Cruises's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.
What is a 22-night cruise like?: A 22-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from MSC Virtuosa. Pack for both formal nights and casual deck days.