Rotterdam 21-night 21-Day Mediterranean & Greek Isles: Istanbul Overnight from Barcelona, Oct 27, 2027

Holland America Line · Rotterdam · Oct 27, 2027 – Nov 17, 2027

Visit Barcelona, Palma de Mallorca, Marseille (Provence), Livorno (Florence), Civitavecchia (Rome) and 9 more ports

Departure Barcelona
Return Piraeus (Athens), Greece
Duration 21 Nights
From $4509 pp

Itinerary

  1. Day 1
    Barcelona Arrives 12:00 AM · Departs 4:00 PM
  2. Day 2
    Palma de Mallorca Arrives 8:00 AM · Departs 9:00 PM
  3. Day 3
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  4. Day 4
    Marseille (Provence) Arrives 7:00 AM · Departs 4:00 PM
  5. Day 5
    Livorno (Florence) Arrives 8:00 AM · Departs 8:00 PM
  6. Day 6
    Civitavecchia (Rome) Arrives 7:00 AM · Departs 8:00 PM
  7. Day 7
    Naples (Pompeii) Arrives 8:00 AM · Departs 7:00 PM
  8. Day 8
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  9. Day 9
    Kerkira (Corfu) Arrives 8:00 AM · Departs 5:00 PM
  10. Day 10
    Kotor Arrives 8:00 AM · Departs 5:00 PM
  11. Day 11
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  12. Day 12
    Piraeus (Athens), Greece Arrives 8:00 AM · Departs 5:00 PM
  13. Day 13
    Mykonos Arrives 7:00 AM · Departs 8:00 PM
  14. Day 14
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  15. Day 15
    Istanbul Arrives 7:00 AM · Departs 12:00 AM
  16. Day 16
    Istanbul Arrives 12:00 AM · Departs 11:00 PM
  17. Day 17
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  18. Day 18
    Kusadasi (Ephesus), Turkey Arrives 7:00 AM · Departs 7:00 PM
  19. Day 19
    Kos Arrives 8:00 AM · Departs 6:00 PM
  20. Day 20
    Rhodes Arrives 8:00 AM · Departs 9:00 PM
  21. Day 21
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  22. Day 22
    Piraeus (Athens), Greece Arrives 7:00 AM · Departs 12:00 AM

Cabin Prices

Prices as of 2026-10-19.

Prices per person, based on double occupancy in USD.

Inside $4509
Ocean View $5029
Balcony $5309
Suite $7399

Ports of Call

  • Barcelona
  • Palma de Mallorca
  • Marseille (Provence)
  • Livorno (Florence)
  • Civitavecchia (Rome)
  • Naples (Pompeii)
  • Kerkira (Corfu)
  • Kotor
  • Piraeus (Athens), Greece
  • Mykonos
  • Istanbul
  • Kusadasi (Ephesus), Turkey
  • Kos
  • Rhodes

About This Cruise

21-night Holland America Line Rotterdam cruise from Barcelona to Palma de Mallorca, Marseille (Provence), Livorno (Florence) and Civitavecchia (Rome)…

Cruise Line Holland America Line
Ship Rotterdam
21-Day Mediterranean & Greek Isles: Istanbul Overnight cruise ship Rotterdam

Frequently asked questions

What is included in the cruise fare?
Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.
How far in advance should I book this cruise?
For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on Rotterdam.
What documents do I need to board?
Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Barcelona may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.
Can I change or cancel my booking?
Change and cancellation policies depend on Holland America Line's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.
What is a 21-night cruise like?
A 21-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from Rotterdam. Pack for both formal nights and casual deck days.