What is included in the cruise fare?

Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.

How far in advance should I book this cruise?

For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on Seven Seas Prestige.

What documents do I need to board?

Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Panama City, Panama may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.

Can I change or cancel my booking?

Change and cancellation policies depend on Regent Seven Seas Cruises's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.

What is a 12-night cruise like?

A 12-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from Seven Seas Prestige. Pack for both formal nights and casual deck days.

Seven Seas Prestige 12-night Panama City to Miami, FL from Panama City, Panama, Mar 14, 2028

Regent Seven Seas Cruises · Seven Seas Prestige · Mar 14, 2028 – Mar 26, 2028

Visit Panama City, Panama, Panama Canal, Cartagena, Colombia, Oranjestad, Willemstad and 3 more ports

Departure Panama City, Panama

Return Miami

Duration 12 Nights

From $7699 pp

Itinerary

Day 1

Panama City, Panama Arrives 12:00 AM · Departs 4:00 PM
Day 2

Panama Canal Arrives 6:00 AM · Departs 7:00 PM
Day 3

Cartagena, Colombia Arrives 12:01 PM · Departs 8:00 PM
Day 4

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 5

Oranjestad Arrives 7:00 AM · Departs 5:00 PM
Day 6

Willemstad Arrives 7:00 AM · Departs 5:00 PM
Day 7

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 8

St. Georges, Grenada Arrives 7:00 AM · Departs 5:00 PM
Day 9

At Sea Arrives 7:00 AM · Departs 4:00 PM
Day 10

St. Thomas Arrives 9:00 AM · Departs 5:00 PM
Day 11

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 12

At Sea Arrives 12:00 AM · Departs 12:00 AM
Day 13

Miami Arrives 7:00 AM · Departs 12:00 AM

Cabin Prices

Prices as of 2026-10-19.

Prices per person, based on double occupancy in USD.

Suite $7699

Ports of Call

Panama City, Panama
Panama Canal
Cartagena, Colombia
Oranjestad
Willemstad
St. Georges, Grenada
St. Thomas
Miami

About This Cruise

12-night Regent Seven Seas Cruises Seven Seas Prestige cruise from Panama City, Panama to Panama Canal, Cartagena, Colombia, Oranjestad and Willemstad…

Cruise Line Regent Seven Seas Cruises

Ship Seven Seas Prestige

Frequently asked questions

What is included in the cruise fare?: Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.
How far in advance should I book this cruise?: For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on Seven Seas Prestige.
What documents do I need to board?: Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Panama City, Panama may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.
Can I change or cancel my booking?: Change and cancellation policies depend on Regent Seven Seas Cruises's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.
What is a 12-night cruise like?: A 12-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from Seven Seas Prestige. Pack for both formal nights and casual deck days.