Seven Seas Prestige 12-night Miami to Panama City from Miami, Mar 2, 2028

Regent Seven Seas Cruises · Seven Seas Prestige · Mar 02, 2028 – Mar 14, 2028

Visit Miami, Key West, George Town, Cayman Islands, Falmouth, Jamaica, Cabo Rojo and 4 more ports

Departure Miami
Return Panama City, Panama
Duration 12 Nights
From $7549 pp

Itinerary

  1. Day 1
    Miami Arrives 12:00 AM · Departs 4:00 PM
  2. Day 2
    Key West Arrives 8:00 AM · Departs 4:00 PM
  3. Day 3
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  4. Day 4
    George Town, Cayman Islands Arrives 8:00 AM · Departs 5:00 PM
  5. Day 5
    Falmouth, Jamaica Arrives 8:00 AM · Departs 5:00 PM
  6. Day 6
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  7. Day 7
    Cabo Rojo Arrives 8:00 AM · Departs 5:00 PM
  8. Day 8
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  9. Day 9
    Cartagena, Colombia Arrives 8:00 AM · Departs 5:00 PM
  10. Day 10
    At Sea Arrives 12:00 AM · Departs 12:00 AM
  11. Day 11
    Puerto Limon Arrives 8:00 AM · Departs 5:00 PM
  12. Day 12
    Panama Canal Arrives 6:00 AM · Departs 7:00 PM
  13. Day 13
    Panama City, Panama Arrives 7:00 AM · Departs 4:00 PM

Cabin Prices

Prices as of 2026-10-20.

Prices per person, based on double occupancy in USD.

Suite $7549

Ports of Call

  • Miami
  • Key West
  • George Town, Cayman Islands
  • Falmouth, Jamaica
  • Cabo Rojo
  • Cartagena, Colombia
  • Puerto Limon
  • Panama Canal
  • Panama City, Panama

About This Cruise

12-night Regent Seven Seas Cruises Seven Seas Prestige cruise from Miami to Key West, George Town, Cayman Islands, Falmouth, Jamaica and Cabo Rojo…

Cruise Line Regent Seven Seas Cruises
Ship Seven Seas Prestige
Miami to Panama City cruise ship Seven Seas Prestige

Frequently asked questions

What is included in the cruise fare?
Standard cruise fares include your cabin, onboard meals at main dining venues, most non-specialty entertainment, use of pools and common facilities, and transport between ports of call. Gratuities, specialty dining, alcoholic drinks, shore excursions and onboard spa services are typically billed separately.
How far in advance should I book this cruise?
For popular sailings, booking 6–12 months ahead typically gives the best cabin selection and fares. Last-minute discounts can appear 30–60 days before departure when the cruise line wants to fill remaining cabins on Seven Seas Prestige.
What documents do I need to board?
Most international itineraries require a passport valid for at least six months beyond your return date. Closed-loop sailings that depart and return to the same U.S. port from Miami may accept a government-issued photo ID plus a certified birth certificate for U.S. citizens — always verify with the cruise line.
Can I change or cancel my booking?
Change and cancellation policies depend on Regent Seven Seas Cruises's fare type and how close you are to departure. Refundable deposits typically allow changes up to the final-payment date without penalty; closer to sailing, cancellation fees scale up. Review the specific fare rules before booking.
What is a 12-night cruise like?
A 12-night cruise balances relaxing sea days with active port days. You can expect a mix of onboard programming — dining, entertainment, spa and fitness — and multiple shore excursions from Seven Seas Prestige. Pack for both formal nights and casual deck days.